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您现在的位置:首页 > 产品中心 > 细胞库 > 人肿瘤细胞、癌细胞 > HTB-11SK-N-SH 人神经母细胞瘤细胞

SK-N-SH 人神经母细胞瘤细胞

  • 更新时间:  2020-09-12
  • 产品型号:  HTB-11
  • 简单描述
  • SK-N-SH 人神经母细胞瘤细胞
    原代细胞|细胞系|细胞株|菌种;细胞库管理规范,提供的细胞株背景清楚,提供参考文献和Z优培养条件!
详细介绍

 SK-N-SH 人神经母细胞瘤细胞

ATCC® Number:HTB-11™    Price:$276.00
Designations:SK-N-SH
Depositors: G Trempe, LJ Old
Biosafety Level:1
Shipped:frozen
Medium & Serum:See Propagation
Growth Properties:adherent
Organism:Homo sapiens (human)
Morphology:epithelial
 SK-N-SH 人神经母细胞瘤细胞
Source:Organ: brain 
Disease: neuroblastoma 
Derived from metastatic site: bone marrow
Cellular Products:plasminogen activator 
shows increased expression of M-CSF after treatment with amyloid-beta peptide
Permits/Forms:In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimay responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location.
 
Restrictions:The cells are distributed for research purposes only. The Memorial Sloan-Kettering Cancer Center releases the line subject to the following: 1.) The cells or their products must not be distributed to third parties. Commercial interests are the exclusive property of Memorial Sloan-Kettering Cancer Center. 2.) Any proposed commercial use of these cells must first be negotiated with The Director, Office of Industrial Affairs, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021; phone (212) 639-6181; (212) 717-3439.
Applications:transfection host (Nucleofection technology from Lonza)
Antigen Expression:Blood Type A; Rh+
DNA Profile (STR):Amelogenin: X 
CSF1PO: 11 
D13S317: 11 
D16S539: 8,13 
D5S818: 12 
D7S820: 7,10 
THO1: 7,10 
TPOX: 8,11 
vWA: 14,18
Cytogenetic Analysis:The cell line is hyperdiploid human female (XX), with the modal chromosome number of 47. Normal chromosomes N9 and N22 are single. One copy of each of these chromosomes is structurally altered to form the two marker chromosomes 9q+ and 22q+., Chromosomes N7 is trisomic. Extra bands were found on one copy of chromosome N7, thereby forming a marker chromosome as described by R.C. Seeger. May have been translocated in part(s) to the q arms of chromosomes N9 and N22.
Isoenzymes:AK-1, 1 
ES-D, 1
G6PD, B
GLO-I, 1 
Me-2, 2 
PGM1, 1 
PGM3, 1
Age:4 years
Gender:female
Comments:The SK-N-SH line was developed by J.L. Biedler and differs from SK-N-MC (see ATCC HTB-10) in that it exhibits a longer doubling time and higher levels of dopamine - beta - hydroxylase. 
SK-N-SH has been used as a target cell line in cell mediated cytotoxicity assays.
Propagat 
Ref 

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