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您现在的位置:首页 > 产品中心 > 细胞库 > 人肿瘤细胞、癌细胞 > CRL-1420MIA PaCa-2 人胰腺癌细胞

MIA PaCa-2 人胰腺癌细胞

  • 更新时间:  2020-09-10
  • 产品型号:  CRL-1420
  • 简单描述
  • CRL-1420 MIA PaCa-2 人胰腺癌细胞
    ATCC 细胞|细胞系|细胞株|肿瘤细胞|细胞;细胞库管理规范,提供的细胞株背景清楚,提供参考文献和Z优培养条件!
详细介绍

CRL-1420  MIA PaCa-2 人胰腺癌细胞 的介绍

ATCC® Number: CRL-1420™ Price: $279.00
Designations: MIA PaCa-2
Depositors: A Yunis
Biosafety Level: 1
Shipped: frozen
Medium & Serum: See Propagation
Growth Properties: adherent, single cells and loosely attached clusters
Organism: Homo sapiens (human)
Morphology: attached epithelial with floating rounded cells

Source: Organ: pancreas
Disease: carcinoma
Cellular Products: human colony stimulating factor, subclass I (CSF-I); plasminogen activator
Permits/Forms: In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimay responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location.

Isolation: Isolation date: 1975
DNA Profile (STR): Amelogenin: X
CSF1PO: 10
D13S317: 12,13
D16S539: 10,13
D5S818: 12,13
D7S820: 12,13
THO1: 9,10
TPOX: 9
vWA: 15
Cytogenetic Analysis: This is a hypotriploid human cell line. The modal chromosome number is 61. Sixteen to 20 marker chromosomes are commonly found in a cell. A few normal chromosomes are absent.
Isoenzymes: G6PD, B
Age: 65 years
Gender: male
Ethnicity: Caucasian
Comments: The MIA PaCa-2 cell line was established by A. Yunis, et al. in 1975 from tumor tissue of the pancreas obtained from a 65-year-old Caucasian male. [58034]
The established cell line reportedly has a doubling time of about 40 hours and a colony-forming efficiency in soft agar of approximay 19%. [58034]
Hybridomas have been made against the CSF-I produced by this line ATCC HB-8207 
References: 1057: Wu M, et al. Purification and characterization of a plasminogen activator secreted by cultured human pancreatic carcinoma cells. Biochemistry 16: 1908-1913, 1977. PubMed: 15590
22291: Fountzilas G, et al. Comparative effects of selected drug combinations on the growth of a human pancreatic carcinoma cell line (MIA PaCa-2). J. Natl. Cancer Inst. 76: 37-43, 1986. PubMed: 3455740
49623: Robertson JF, et al. Effect of gastrointestinal hormones and synthetic analogues on the growth of pancreatic cancer. Int. J. Cancer 63: 69-75, 1995. PubMed: 7558455
CRL-1420  MIA PaCa-2 人胰腺癌细胞


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